January 02, 2011

I'm Selling 'Transmembrane Voltage Gated Ion Channels'

And everybody wants some of that! Call me crazy, but I'm going into the Kava business. I've always wanted to have my own natural product product, and now I'm going to do that.

I really like wanting to create something that inspires me, that seems outside of my regular or expected framework for living, and then doing it. I like just as much saying that "I did that" when I do it. It's empowering.

I am going to import type of instant Kava from Vanuatu... I don't even know where Vanuatu is, but it sounds nice.

Kava, for all you novices out there (and there are probably a lot) is a root, a plant, a nice relaxing, happiness inducing plant from the pacific islands. In many cultures they do a Kava ceremony where people gather, sit and drink. It's said that bringing Kava to a gathering like a business meeting or a family/relationship gathering will promote peace and open communication, plus it's so fun to drink b/c it numbs the mouth. That's the 'Kavalactones' or chemical compounds in the Kava that cause the relaxing.

So, keep an eye out for any introduction specials, Ill probably make a video to promote it too... The kind that I am getting is made through a special process in Vanuatu where the kava is juiced and the juice dehydrated so the Kava will dissolve almost instantly.

This is what Wikipedia has to say about the Pharmacology,

Pharmacodynamics

Effects of kavalactones include mild sedation, a slight numbing of the gums and mouth, and vivid dreams. Kava has been reported to improve cognitive performance and promote a cheerful mood.[12] Muscle relaxantanaestheticanticonvulsive and anxiolytic effects are thought to result from direct interactions of kavalactones with voltage-gated ion channels.[13]Research currently suggests that kavalactones potentiate GABAA activity but do not alter levels of dopamine and serotonin in the CNS.[14] Heavy, long-term kava use does not cause any reduction of ability in saccade and cognitive tests but is associated with elevated liver enzymes.[15]
Desmethoxyyangonin, one of the six major kavalactones, is a reversible MAO-B inhibitor (Ki 280 nM)[16] and is able to increase dopamine levels in the nucleus accumbens. This finding might correspond to the slightly euphoric action of kava.[17]
Kavain, in both enantiomeric forms, inhibits the reuptake of noradrenalin at the transporter (NAT), but not of serotonin (SERT).[18] An elevated extracellular noradrenalin level in the brain may account for the reported enhancement of attention and focus.


The reference to the title above has to do with electrical charges between axons and synapses in the brain, it's all very chemical...

B~

2 comments:

  1. Sounds very interesting! Hope it goes well.
    Love you, Mom

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  2. Vanuatu, officially the Republic of Vanuatu, is an island nation located in the South Pacific Ocean. The archipelago, which is of volcanic origin, is some 1,750 kilometres (1,090 mi) east of northern Australia, 500 kilometres (310 mi) northeast of New Caledonia, west of Fiji, and southeast of the Solomon Islands, near New Guinea.

    There!! Now you know where Vanuatu is!!!

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